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Phytoplanktonic organisms have an important effect on the quality of water. Algal blooms may occur in freshwater as well as marine environments. With the global expansion of harmful algal blooms (HABs), several approaches have been undertaken to monitor its occurrence. The dinoflagellates and diatoms are the most represented phylum and both can to produce a negative impact if they are present in densities that would cause HABs with consequent health and economic impact on the local population. The reasons for HABs remain debated and include not only eutrophication, their occurrence in some locations appears to be entirely natural, while in others they appear to be a result of human activities. There is an increase of monitoring plans in the world (expanding routine coastal monitoring programs, deployment of new detection methods for individual species, for toxins and toxicities) resulting from the increased impact from these HABs. During the last decade, benthic dinoflagellates of the genus Ostreopsis have expanded their distribution from tropical– subtropical to temperate waters, such as the Mediterranean Sea.