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Transfusion Dependent Homozygous α-Thalassemia

Alpha-thalassemia results from a dysfunction of the α-globin gene. Types of mutations include large deletions and point mutations. The most severe form of α-thalassemia is hydrops fetalis, which is caused by homozygosity of certain types of either deletion or point mutations, and some cases were the results of a combination of both.

Citation: Hassan S, Ahmad R, Hamid FSA, Aziz NA,Lazira S, et al. (2015) Transfusion Dependent Homozygous a-Thalassemia in Patients Associated with Hypospadias in Three Survivors. J Blood Disorders Transf 6:248.doi: 10.4172/2155-9864.1000248
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