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Prochlorperazine maleate [2-chloro-10-[3-(4-methyl-1- piperazinyl) propyl]-10H-phenothiazine (Z)-2- butenedioate (1:2)] is a phenothiazine derivative used as an anti-emetic. It has a prominent antiemetic activity and is most often used for the (short-time) treatment of nausea, vomiting and vertigo. A recent research about emergency department treatment of migraine headache indicated that prochlorperazine was statistically superior to octreotide in clinical success rate and pain relief in migraine patients.
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