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Evaluation of Nootropic and Anti-Nociceptive Activity of Green Tea in Comparison with Medhya Rasayana

Green tea (Camellia sinesis) is a known traditional medicinal plant that has been consumed for its putative nutritional and health benefits for centuries. The polyphenols found in green tea are epicatechin, epicatechin-3- gallate, epigallocatechin, and epigallocatechin-3-gallate (EGCG), comprise 30-40 percent of the extractable solids of dried green tea leaves. Green tea polyphenols have demonstrated significant antioxidant activity. In the present study aqueous extract of green tea (10 ml/kgp.o), methanolic extract of green tea (5 ml/kg p.o) and standard Piracetam (150 mg/kg body weight p.o) were used to evaluate the Nootropic activity. Its behavioral studies on mazes like Elevated plus Maze, Morris Water Maze and avoidance behavior on step down type passive avoidance models were performed, whole brain acetyl cholinesterase enzyme activity was also estimated.

 

Citation: Sharadha S, Joel C, Prathyusha K, Krishnamohan G, Uma Maheswara Rao V (2014) Evaluation of Nootropic and Anti-Nociceptive Activity of Green Tea in Comparison with Medhya Rasayana . Chem Sci J 5:82. doi: 10.4172/2150-3494.1000082

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