Osteoprogenitor cells are known to reside within the Marrow Stromal Cells (MSCs) compartment. Since their first isolation in 1968 , MSCs have been largely studied for their cellular identity and differentiation potential, and they became an attractive source of adult stem cells useful for clinical applications. As with any stem cell type, MSCs possess self-renewal ability and the capacity to differentiate along multiple mesenchymal cell lineages, such as bone, cartilage and adipose cells, as well as along non-mesenchymal cell lineages, due to their plasticity
Citation: M Bouche, L Madaro (2014) Invited Commentary on "Enrichment and Characterization of Two Subgroups of Committed Osteogenic Cells in the Mouse Endosteal Bone Marrow with Expression Levels of CD24". J Bone Marrow Res 2:145.