Foetal Alcohol Syndrome Disorder (FASD) is a complex condition resulting from the consumption of alcohol during pregnancy. Diagnosis of prenatal exposure to alcohol depends on questionnaire about consumption, biomarkers in neonatal alternative matrices as maternal hair and neonatal meconium, and postnatal clinical data as facial features. However, biomarkers of cellular damage due to exposure to alcohol during pregnancy are lacking. Prenatal alcohol exposure can lead to altered placental cellular function, resulting in changes in hormone production. Herein, the alteration in the synthesis of this hormonal output was studied using a cultured human trophoblast cell line (JEG3).
Citation: Clave S, Joya X, Salat-Batlle J, Martinez SE, Garcia-Algar O, et al. (2014) Effects of Ethanol Sustained Exposure on Human Trophoblast Cell Hormonal Production. J Steroids Horm Sci 5:121. doi: 10.4172/2157-7536.1000121