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Using the traditional treatment techniques, radiation oncologists have to contend with variations in tumor position during the treatment by treating a margin of healthy tissue around the tumor. Significant tumor motion, which can be up to 5 cm, has been induced mostly by cardiac and respiratory motion. To accommodate this undesired movement and other errors; physicians incorporate a large margin around the tumor to delineate Planning Target Volume (PTV), so that the cancerous Clinical Target Volume (CTV) receives the prescribed radiation dose under any scenario during treatment session. Consequently, a large volume of healthy tissue is included in the PTV and sometimes it is difficult to spare critical organs adjacent to the tumor.
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