alexa Nutrition, Genes and Modern Disease: A Current Dilemma or a Legacy of our Past

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Nutrition, Genes and Modern Disease: A Current Dilemma or a Legacy of our Past

Contemporary humans are genetically adapted to the environment that their ancestors survived in and that consequently selected their genetic makeup. Since the agricultural revolution some 10,000 years ago, the lifestyles and dietary requirements of modern humans have changed dramatically. It is suggested that these changes have occurred too recently on an evolutionary time scale for the modern human genome to adapt. Therefore, our ancestral genome is ill-suited for our current modern consumption and existence, and thus contributes to diseases associated with contemporary lifestyles, such as cardiovascular disease, obesity and type 2 diabetes. It is therefore suggested that a diet similar to our ancestors could circumvent many of our modern illnesses and serve as a reference for better nutrition, health, and longevity. Although this model should certainly be commended for its simplistic dietary practices that no doubt improve health and well-being; its premise is cemented in the thrifty genome hypothesis and the fact that humans are modern hunters and gatherers whose genome is ill-suited for modern diets.

Citation: Myers S, Williamson S (2014) Nutrition, Genes and Modern Disease: A Current Dilemma or a Legacy of our Past. J Diabetes Metab 5:393.

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