Meta Description: Fetal-neonatal complications are directly related to inadequate glycemic control during key periods of pregnancy. Poor periconceptional and early first trimester glycemic control are related to spontaneous abortions, early growth delay, and major congenital malformations.

Fetal-neonatal complications are directly related to inadequate glycemic control during key periods of pregnancy. Poor periconceptional and early first trimester glycemic control are related to spontaneous abortions, early growth delay, and major congenital malformations. During the second trimester, it is predictive of Pregnancy Induced Hypertension, preterm labor and delivery and minor congenital anomalies. During the third trimester of pregnancy it is predictive of macrosomia, birth trauma, fetal dystocia, maternal trauma and high cesarean delivery rate.

It is also associated with complications linked to fetal hyperinsulinism such as neonatal hypoglycemia , respiratory distress, cardiac Asymmetric Septal Hypertrophy, and to decreased fetal oxygenation and its acute or chronic complications such as neonatal polycythemia or thrombocytopenia. Finally, hyperglycemia in labor aggravates the risk of neonatal hypoglycemia and is associated with lowered apgar scores.

For more details: https://www.omicsonline.org/open-access/neonatal-management-of-the-infant-of-diabetic-mother-2161-0665-4-186.php?aid=21675

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