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Enteric cells, isolated from intestinal smooth muscle strips, were transplanted into the syngeneic rodent stomach in collagen gel with and without basic fibroblast growth factor (bFGF). While growth factor delivery did not affect cell viability after transplantation, bFGF promoted the formation of numerous ganglion-like structures at the injection site and adjacent muscularis. Immunohistochemistry staining revealed the presence of peripherin, S100, and synaptophysin in these ganglion-like structures.
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