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S. aureus causes superficial to deep seated infections in human beings. Methicillin-resistant Staphylococcus arueus (MRSA) evolved in the 1960s and since then has become a worldwide concern owing to increasing morbidity and mortality in health-care settings and even community. (MRSA) is a resistant variant of S. aureus which are resistant to beta-lactum antibiotics and other classes of antimicrobials. Early and accurate detection of MRSA and their antimicrobial susceptibility profile is therefore imperative for the selection of appropriate antimicrobial therapy.