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Tadpoles from populations close to farm fields are more resistant to chlorpyrifos -- one of the most commonly applied insecticides in the world, often sold as Dursban or Lorsban. Wood frogs living close to agricultural land were more likely to have been exposed to pesticides for many generations compared to those living far from agriculture; the latter frog populations likely experienced little or no exposure to pesticides. Wood frogs living close to agricultural land were more likely to have been exposed to pesticides for many generations compared to those living far from agriculture. Using three commonly applied pesticides that have similar chemical properties chlorpyrifos, carbaryl, and malathion 15 populations were exposed to high concentrations of each insecticide. Thewood frog populations with resistance to one insecticide also had resistance to the other insecticides.