Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.
Scaevola spinescens (Goodeniaceae) has been traditionally used by indigenous Australians to treat various ailments including cancer, thus it is necessary to identify optimum extraction conditions for bioactive components from this plant. This study investigated the effects of different extraction conditions on Total Phenolic Content (TPC), antioxidant capacity (ABTS, DPPH, CUPRAC, FRAP assays) and anti-cancer activity (MTT assay) of S. spinescens. The results showed that optimal extraction conditions for TPC using water were 80°C, 15 min and ratio of 20:1 mL/g. However, the aqueous extract prepared under optimal conditions had lower TPC and less antioxidant capacity than those of the organic solvent extracts. The acetone extract displayed the greatest TPC as well as the highest antioxidant capacity and anti-cancer activity against a panel of cancer cell lines, including cancers of the pancreas, breast, lung, brain, skin, colon and ovary. Therefore, further investigations should be conducted to identify key bioactive compounds as potential anti-cancer agents.
Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi