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Inactivation of Endotoxin and Lipid A by Nitrogen Gas Plasma Exposure Running title: Inactivation Endotoxin and lipid A

It was confirmed that the degree of endotoxin inactivation was more than 5 log reduction in 30 minutes by nitrogen gas plasma (Figure 1) and that by SteradR was around l log reduction, indicating under experimental conditions, performance characteristics of nitrogen gas plasma was superior to those of SteradR using hydrogen peroxide gas plasma. SteradR is not true gas plasma sterilization. Our method of endotoxin inactivation was conducted using nitrogen gas plasma exposure. Concerning Pub Med research or Google research with key words of endotoxin, gas plasma, inactivation or depyrogenation, it is only a few articles to be matched, respectively, indicating gas plasma study of endotoxin inactivation/depyrogenation was very limited.

Citation: Shintani H (2015) Inactivation of Endotoxin and Lipid A by Nitrogen Gas Plasma ExposureRunning title: Inactivation Endotoxin and lipid A. Pharmaceut Reg Affairs 4: 129.

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