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One of the reasons that cholera has been prevalent for much of human history is because the main reservoirs of V. cholerae are people together with aquatic sources such as brackish water and estuaries. The bacterium is invariably found in association with copepods or other zooplankton, shellfish, and aquatic plants, especially in relatively warm water. Given this synergy with people, the relationship between people and the disease is hard to disassociate.
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