alexa Novel Upconversion Fluorescent Probe for Schistosoma japonicum Cercariae Imaging

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Novel Upconversion Fluorescent Probe for Schistosoma japonicum Cercariae Imaging

Schistosomiasis has influence on people’s security and daily life significantly, while cercarial stage of the schistosome life-cycle is the only infectious period. To detect cercarial efficiently, we synthesized rare-earth upconversion nanophosphors UCs-Ni loaded with niclosamide. The fluorescence of UCs-Ni was demonstrated by the fluorescence emission spectra. The cell imaging test illustrated that UCs-Ni was biocompatible, cell-permeable and suitable for cercariae imaging. When it has been utilized for cercariae imaging, we found that the UCs-Ni could penetrate into cercariae.

Citation: Fan Y, Xie Y, Chen L, Liu W, Li X, et al. (2015) Novel Upconversion Fluorescent Probe for Schistosoma japonicum Cercariae Imaging. Med chem 5:231-234. doi: 10.4172/2161-0444.1000269

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