alexa Clinical Usefulness of Combination Therapy with Minocycline and Ciprofloxacin as a Treatment for Fulminant Cases

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Clinical Usefulness of Combination Therapy with Minocycline and Ciprofloxacin as a Treatment for Fulminant Cases

Japanese spotted fever (JSF) is a member of the spotted fever group rickettsiosis caused by Rickettsia japonica. JSF is transmitted by tick-bite, and clinically characterized with fever, cutaneous eruption (exanthematous legions), and inoculation eschar. Diagnosis of JSF is generally based on clinical presentations, followed by serological confirmation using paired (acute- and convalescent-phase) serum.

 
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