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Test of Clostridium Difficile Toxin

Tests to detect Clostridium difficile and its toxins are used to diagnose diarrhoea and other conditions and complications caused by toxin-producing C. difficile. Conditions resulting from this bacterial infection include pseudomembranous colitis, in which dead tissue, fibrous protein, and numerous white blood cells form a lining over the surface of the inflamed bowel, toxic megacolon, and perforated bowel. Testing may also be ordered to detect recurrent disease. If tests for C. difficile and C. difficile toxin are positive, it is likely that the person's diarrhea and related symptoms are due to the presence of toxin-producing C. difficile. Negative test results for both the bacteria and the toxin may mean that the diarrhea and other symptoms are being caused by something other than C. difficile.

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