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Over the past 15 years the incidence of hepatocellular carcinoma [HCC] has more than doubled. Every year there are 500,000 new cases in the Asia–Pacific region, often due to chronic hepatitis B virus [HBV] infection [1]. More than 60% of the total number of HCC cases occurs in China alone and an estimated 360,000 patients residing in Far East countries, including China, Japan, Korea and Taiwan, die from this disease each year. In Japan hepatitis C virus [HCV]-related HCC represents 70% of all cases .
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