Abstract Hand grip is the functional unit of dentists used in firm holding of instruments and tools .Muscles of hand grip supplied by cervical nerves. Dentists put their neck in high physical load for prolonged time that lead to neck pain. 54.4% of dentists in K.S.A. have neck pain and 21% drop out of their job. Objective: The main objective is to find the correlation between neck pain and hand grip in dentists of Saudi Arabia. Methodology: Subjects: 25 chronic neck pain dentists (suffering from neck pain more than 3 months) in both gender, will be selected non randomly. Their ages ranged from 25 to 40 years with normal BMI (18.5-25) will be divided into subgroups according to neck position during their work. Procedures: Pain intensity will be determined by visual analog scale (VAS), hand grip strength will be measured by Jamar hand dynamometer in kilogram (Kg) unit. Result: Among 25 dentists the result showed extremely significant correlation between neck pain and hand grip strength (direct proportional). The p value (0.0001). Discussion and conclusion: the direct proportional between neck pain and hand grip strength is due to sensory motor integration deficit or due to neuro hyper excitability.