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Potential Role of Pharmacogenetic Testing in Clinical Care: Warfarin and Clopidogrel

The numbers are staggering.According to the Institute of Medicine (IOM), at least 1.5 million Americans are injured each year by medication mistakes and every hospital patient is exposed to at least one medication error each day (National Institute of Medicine. Preventing Medication Errors. Washington, DC: National Academy of Sciences; 2007). An estimated 7,000 people die each year from a medication error.In addition to the health toll this takes on the patient and the cost of human life, this situation is costing the healthcare system an estimated $21 billion annually in wasteful spending.The average senior is taking anywhere from 8-12 different medications per day. One possible, yet controversial solution to this problem has been the use of DNA testing to determine who is most at risk of suffering an Adverse Drug Event (ADE) based upon the way they metabolize the nation’s most popularly used medications.

Citation: Shawaqfeh MS (2015) Potential Role of Pharmacogenetic Testing in Clinical Care: Warfarin and Clopidogrel. Cardiol Pharmacol 4:138.

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