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In the past decades, research efforts in microfluidics – an enabling technology to perform automated operations on fluid using submicroliter volumes – have rapidly expanded in terms of both theoretical studies and applications. Microfluidic devices can handle small volume of fluids, extending down to attoliter-scale volumes in forms of droplets or liquid sections in confined micro-channels, which can be applied a large variety of biological solutions (e.g. enzymes, nucleic acids, antibodies or cells).
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