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Gastric carcinoma shows declining incidence in last year’s, it is one of the gastrointestinal cancer with high morbidity and mortality. World Health Organization (WHO) was classified the gastric adenocarcinoma into four predominant histological types. These are tubular adenocarcinoma, papillary adenocarcinoma, mucinous adenocarcinoma (MAC) and signet ring cell carcinoma. SRCC is a descriptive term used for a specific type of mucin-producing adenocarcinoma. Intracytoplasmic mucin pushes the nuclei one side of cell and cause the typical appearance of signet ring in these tumor cells. Approximately 95 % of SRCC originates from stomach. Submit your manuscripts at http://www.scitechnol.com/submitmanuscript-clinical-experimental-oncology.php