Male lower urinary tract symptoms (LUTS) encompass a variety of urologic symptoms including increased obstructive and storage symptoms. The prevalence of LUTS increases with age . In the United States in 2000, 4.5 million visits to physicians for LUTS diagnosis occurred with total treatment costs of 1.3 billion dollars . In spite of the high number of affected individuals and the cost of their health care, the underlying cause(s) of age related male LUTS remains controversial and is often attributed to benign prostatic hyperplasia (BPH).
Citation: Podlasek CA, Bond CW, Tang Y, Marr L, Angeloni N, et al. (2012) Analysis of Changes in Nitric Oxide Synthase Signaling in BB/WOR Diabetic Prostate. Androl Open Access 1:101. doi: 10.4172/2167-0250.1000101