alexa Critical Role of Calpain in Cell Proliferation

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Critical Role of Calpain in Cell Proliferation

Calpain is a conserved family of calcium-dependent, cytosolic, neutral cysteine proteases. The best characterized members of the family are the ubiquitously expressed calpain 1 and calpain 2. They perform controlled proteolysis of their target proteins. The regulation of these enzymes includes autolysis, calcium, phosphorylation as a posttranslational modification, and binding of calpastatin, phospholipids or activator proteins, respectively.

Citation: Kovacs L, Su Y (2014) The Critical Role of Calpain in Cell Proliferations. J Biomol Res Ther 3:112.

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