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A Vero cell-derived, inactivated and alum-adjuvanted JE vaccine based on the SA 14-14-2 strain was approved in 2009 in North America, Australia and various European countries. The primary two doses are administered 4 weeks apart. A booster dose is recommended 1–2 years after the primary immunization. This vaccine has been given concomitantly with hepatitis A vaccine without significant interference with the safety and immunogenicity of either vaccine. Data on concomitant administration with other vaccines frequently used in travellers are currently unavailable.
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