Non-alcoholic fatty liver disease (NAFLD) is considered the most common cause of chronic liver disease in the world with an estimated prevalence of 20-30% in the United States and other Western populations. NAFLD is a slowly progressive disease and encompasses a spectrum of varying liver histology, ranging from simple steatosis to hepatocyte necro-apoptosis, and non-alcoholic steatohepatitis (NASH) which leads to variable grades of fibrosis and ultimately cirrhosis with its complications including hepatocellular carcinoma (HCC)

Amin MA, Ashmawi K, Shakr O, Mussa S, Samie RMA, et al. (2015) Serum Adipokines in Patients with Non-alcoholic Fatty Liver Disease - Is there a Role for Predicting the Severity of Liver Disease? Intern Med 4:191.

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