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Calorie restriction, a practice of reducing calorie intake without malnutrition, is probably one of the best ways to slow down aging. Studies have shown that calorie restriction could, in fact, increase the mean and maximal life span of many species, such as yeast, fish, mice, hamsters, and dogs. The underlying mechanism of this “anti-aging” effect remains unclear. It is possible that the reduction of body fat, reduction in oxidative damage, and improved insulin sensitivity are all key contributors to the extended life span in mammals.
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