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Meta Description: Since the infectious process of caries has been well established in humans one may justify that some kind of host immunity regulates caries activity.
There are many factors responsible for dental caries such as poor oral hygiene, concentration of bacteria in oral cavity with acidophilic activity, hereditary, cariogenic diet and reduced level of fluoride in drinking water. Since the infectious process of caries has been well established in humans one may justify that some kind of host immunity regulates caries activity. Salivary IgA (S-IgA) is the first line of defence of the host against pathogens which invade oral mucosal surfaces. The Salivary-IgA antibodies improve the oral immunity by preventing adherence of microbes, neutralizing enzymes, toxins and viruses; or by acting in synergy with other factors such as lysozyme and lactoferrin.
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