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Blackberry (Rubus sp. var. Loch Ness) Extract Reduces Obesity Induced by a Cafeteria Diet and Affects the Lipophilic Metabolomic Profile in Rats

Blackberries (Rubus sp. var. Loch Ness) contain large amounts of anthocyanins and flavonols, which have several health benefits. The present study was designed to determine the effects of a methanolic blackberry extract in rats fed a cafeteria diet. Weaned female rats were assigned to one of three dietary groups: standard pellet diet (SD), cafeteria diet (CD) and cafeteria diet supplemented with Rubus extract (CRD) for 90 days. Plasma metabolites and insulin were analyzed with commercial kits and fatty acid profile was measured by gas chromatography whereas other aliquots were subjected to metabolomics fingerprinting analysis using ultra high efficiency liquid chromatography.

Blackberry (Rubus sp. var. Loch Ness) Extract Reduces Obesity Induced by a Cafeteria Diet and Affects the Lipophilic Metabolomic Profile in Rats
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