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Poly(γ-glutamic acid) (γ-PGA) has been introduced into sol-gel derived silica to produce an organic/ inorganic hybrid system to improve the toughness of conventional bioactive glass. Since calcium is an important element in bioactive glass for bone regeneration, this work is trying to find a suitable calcium source for this hybrid system and determine how to incorporate the calcium within the γ-PGA hybrid. Calcium chloride and calcium methoxyethoxide (CME) were tested as calcium sources in this work. CME was found to incorporate into the silica network better than calcium chloride at low temperature.
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