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With the significant improvement in the quality of health care and the great advances in the management of pediatric chronic illnesses, long standing psychosocial consequences have been reported in survived chronically ill children. Such children have been found to be more prone to develop different behavioral, emotional, and or psychiatric manifestations compared to their healthy counterparts. The burden of the chronic illness, its treatment, and or the associated impairment of growth and development are the main proposed underlying mechanisms for the occurrence of comorbid psychosocial dysfunction.