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Chitosan Nanoparticles (CSNPs), as drug carrier, can be utilized for enhancing permeability of poorly absorbed drugs. The aim of this work was to enhance the permeability of Ganciclovir (GCV) by loading into CSNPs. An ionic gelation method was undertaken to develop GCV loaded CSNPs. Several process and formulation parameters were screened and optimized through 25-2 fractional factorial design and Box-Behnken design respectively. View more...
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