Clinical data including cognitive scores on Hindi Mental Status Examination (HMSE) of 16 right handed patients with AD visiting geriatric clinic were recorded. Single Photon Emission Computer Tomography (SPECT) was acquired with standard protocol. Region of interest was applied at each of the frontal, temporal, parietal, occipital, cerebellar lobes to measure the regional perfusion. Single Photon Emission Computed Tomography (SPECT) is a minimally invasive imaging tool to study the perfusion pattern of brain using radio tracers. Further it is potentially useful in determining the regional perfusion, regional cerebral blood flow (rCBF) and regional cerebral metabolism. Single Photon Emission Computed Tomography (SPECT) is a minimally invasive imaging tool to study the perfusion pattern of brain using radio tracers. Further it is potentially useful in determining the regional perfusion, regional cerebral blood flow (rCBF) and regional cerebral metabolism. Recent studies have started to throw light on role of small vessel pathology being contributing to the cognitive symptoms in patients with Alzheimer disease. Various vascular pathologies such as cholesterol metabolism pathways (clusterin) vascular risk factors (insulin, hypertension) have been reported to play role in the structural atrophy Alzheimerââ¬â¢s disease.
Srikala Bharath, A retrospective study on relation between cognitive performance and lobar perfusions of brain in Alzheimerââ¬â¢s dementia using Single Photon Emission Computer Tomography
Last date updated on September, 2024
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