|Breast cancer is currently the most common malignancy among women in both developed and developing regions of the world. Although the incidence of breast cancer is higher in developed countries, the majority of mortalities occur in low-income areas where many cases are diagnosed at late stages. Breast cancer has also become an increasing burden in Asian countries, although it has typically been perceived as a âWesternâ disease. More seriously, the rate of breast cancer in Asian women below the age of 40 is higher than in Western women of the same age. Singapore has the highest Age-Standardized Rate (ASR) of breast cancer in Asia. Although the ASR of breast cancer in Singapore is still lower than in the USA, Europe or Australasia, Singapore experienced a three-fold increase in the incidence of breast cancer between 1968 and 2002. Additionally, the incidence of female breast cancer has been steadily increasing in the last decade, from 54.9 per 100,000 in 1998-2002 to 60.0 per 100,000 in 2005-2009 and breast cancer remains the most common cancer among Singaporean females.