Autoimmune disorders are diseases caused by self-antibodies autoantibodies that will attack the person organs cells and tissues. This unusual phenomena starts when the immune system recognize normal body constituents as foreign. The specific cause of autoimmune diseases is not yet known, but there are several factors that will affect this disease such as genetic factors/ predisposition in cases such as rheumatoid arthritis. There are two types of autoimmune disorders, they are systemic autoimmune diseases and localized autoimmune diseases. The treatment strategies for autoimmune diseases are still under investigation and is one of the thrust areas of research for immunology researchers.
âThe question of whether autoimmune diseases (AID) have a genetic link has occupied researchers and clinicians for decades. Mendelian inheritance has been demonstrated for some disorders, others are associated with mutations and polymorphisms in susceptibility genes. Mostly, transmission rates were significantly lower than expected. In such cases, and in disorders with no genetic background, environmental factors seem to influence and/or cause disease onset, progression, and outcomeâ Hedrich CM Genetic Variation and Epigenetic Patterns in Autoimmunity. Journal of clinical and cellular immunology addresses various issues related to autoimmunity, evolution, autoimmune diseases and treatment through our articles.
Last date updated on July, 2014