Pharmacodynamics is the branch of pharmacology that deals with the biochemical and physiological effects of the drugs on the body. In simple words it is defined as the branch that studies what a drug does to the body when it is being administered into the system. These drugs affect the body either by mimicking normal biochemical and or physiological processes or inhibiting those vital processes. These drugs perform their function through its mode of actions like stimulating, depressing, blocking, stabilizing, replacing, etc. Also, they may act as direct independent entities that can cause beneficial chemical reactions as free radical scavenging or harmful chemical reactions like cytotoxicity, irritation, etc. The desired activity of a drug is measured by its successful targeting to structures like cell membrane, ligands, receptors, proteins, ion channels, etc. On the other hand the undesirable effects of a drug include increasing the probability of cell mutations, interactions that are additive or multiplicative, or induced physiological damage or chronic conditions. High-impact journals are those considered to be highly influential in their respective fields. The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field. It is first devised by Eugene Garfield, the founder of the Institute for Scientific Information.The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years.
Last date updated on June, 2014