Pharmacodynamics is the branch of pharmacology that deals with the biochemical and physiological effects of the drugs on the body. In simple words it is defined as the branch that studies what a drug does to the body when it is being administered into the system. These drugs affect the body either by mimicking normal biochemical and or physiological processes or inhibiting those vital processes. These drugs perform their function through its mode of actions like stimulating, depressing, blocking, stabilizing, replacing, etc. Also, they may act as direct independent entities that can cause beneficial chemical reactions as free radical scavenging or harmful chemical reactions like cytotoxicity, irritation, etc. The desired activity of a drug is measured by its successful targeting to structures like cell membrane, ligands, receptors, proteins, ion channels, etc. On the other hand the undesirable effects of a drug include increasing the probability of cell mutations, interactions that are additive or multiplicative, or induced physiological damage or chronic conditions. Scientific journal is a periodical publication intended to further progress of science, usually by reporting novel research. There are thousands of scientific journals in publication, and many more have been published at various points in the past. Most journals are highly specialized, although some of the oldest journals publish articles and scientific papers across a wide range of scientific fields. Scientific journals contain articles that are peer reviewed, to ensure that articles meet the journal's standards of quality, and scientific validity.The publication of the results of research is an essential part of the scientific method. If they are describing experiments or calculations, they must supply enough details that an independent researcher could repeat the experiment or calculation to verify the results. Each such journal article becomes part of the permanent scientific record.
Last date updated on June, 2014