|Drug-induced toxicity is a big issue in the clinical practice. Most drugs may cause adverse drug reactions, in small portion of patients. Understanding the mechanism could help us to predict, prevent, and treat the drug-induced toxicity. Although lots of researches have been done in this field, unfortunately, very few mechanisms are known. In recent couple decades, different omics are used to investigate the mechanism of drug-induced toxicity, for example, genomics and proteomics. These omics could provide us the information at gene and protein level, respectively.
The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field. It is first devised by Eugene Garfield, the founder of the Institute for Scientific Information. The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years.