Drug delivery means approaches, technologies, formulations and systems for transporting a pharmaceutical compound within the body as required to safely achieving its desired therapeutic effect. It may be involved in scientific site-targeting within the body, or it might be involved in facilitating systemic pharmacokinetics; in any case, it is typically concerned with both the quantity and duration of the presence of drug. Drug delivery is approached via a drug's chemical formulation; however it may also involve medical devices or drug-device combination products. Drug delivery is a concept profoundly integrated with dosage form and route of administration, which was sometimes considered as a part of the definition.
Drug delivery technologies improve the efficacy and safety of the product as well as patientâs convenience and compliance by modifying the drug releasing profile, absorption, distribution and elimination. Drug release is from: diffusion, degradation, swelling, and affinity-based mechanisms. New drug molecule development is expensive and time consuming. Different methods such as individualizing drug therapy, therapeutic drug monitoring and dosage titration have been attempted in improving safety efficacy ratio of âoldâ drugs. Drug delivery at controlled rate, targeted delivery and slow delivery are some other attractive methods and have been pursued vigorously.
Last date updated on June, 2014