Drug disposition is the knowledge about the fate of a drug such as its absorption, distribution, metabolism, and excretion, known by the acronym ADME and its pharmacokinetics. The pharmacokinetics describes the rates of these processes and of concentration-time relationships. In preclinical and early clinical drug development, information about the factors influencing drug disposition used to predict drug interaction potential, estimate and understand population pharmacokinetic variability, and select doses for clinical trials.
Review articles are the summary of current state of understanding on a particular research topic. They analyze or discuss research previously published by scientist and academicians rather than reporting novel research results.
Review article comes in the form of systematic reviews and literature reviews and are a form of secondary literature. Systematic reviews determine an objective list of criteria, and find all previously published original research papers that meet the criteria. They then compare the results presented in these papers. Literature reviews, by contrast, provide a summary of what the authors believe are the best and most relevant prior publications.
The concept of ""review article"" is separate from the concept of peer-reviewed literature. It is possible for a review to be peer-reviewed, and it is possible for a review to be non-peer-reviewed.
Last date updated on September, 2014