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Acute Myocardial Infarction

Acute Myocardial Infarction (AMI) is defined as a clinical cardiac event resulting in death of myocardial tissue caused by ischemia. Rapid assessment of these patients is critical to direct further diagnostic and therapeutic strategies. The diagnosis of acute myocardial infarction is based on symptoms, signs and findings on the electrocardiogram but in some patients these findings are nondiagnostic. In this patient population the use of cardiac biomarker which indicates cardiac tissue necrosis, of which troponin and Creatine Kinase Isoenzyme (CKMB) are prefered markers, play a pivotal role. These novel markers allow for rule in of AMI within 3 hours after presentation in majority of patients and offer the opportunity to initiate appropriate, evidence based treatment strategy. An increase in copeptin concentrations after acute myocardial infarction was first reported by khan et al, with highest values reported on day 1 and a subsequent decline over next 3 to 5 days. Sherpa N, Potential Clinical Application of Novel Cardiac Biomarker (Troponin) and Stress Marker (Copeptin) for the Diagnosis of Acute Myocardial Infarction in the Emergency Department
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Last date updated on June, 2014

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