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Early and increased amounts of plasma have been associated with improved survival after penetrating and blunt injury. However, no studies involving burn patients demonstrate the effects of intraoperative plasma administration on postoperative resuscitation requirements. This study examined perioperative transfusion ratios [plasma:RBC (P:R)] and the role of early, aggressive plasma administration in a contemporary burn center. The debate over the ideal large volume resuscitation is fraught with conflicting information and subject to passionate debate. Certainly, tomes could be written about the crystalloid versus colloid discussion itself, but that review is beyond the scope of our study. The question of when to start transfusing plasma and at what ratio to packed cells has also been longstanding. In fact, the debate over proper use of fresh frozen plasma has been ongoing for more than 20 years. After a 10-fold increase in FFP administration between the years of 1974-1984, the National Institutes of Health convened a Consensus Development Conference on Fresh Frozen Plasma. Christopher V. Maani, Intraoperative Plasma: Rbc Ratio Affects Postoperative Coagulopathy And Resuscitation Requirements
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Last date updated on June, 2014