alexa Ethnic Differences In Inflammation|OMICS International|Journal Of Neurology And Neurophysiology

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Ethnic Differences In Inflammatory

Inflammatory bowel diseases include ulcerative colitis (UC) and Crohn’s disease (CD). The etiology of IBD is not fully understood and is influenced by environmental, genetic and immunological factors. The geographic variation of IBD is well known. The highest prevalence rates are reported in North America and Northern Europe, whereas the prevalence rates are much lower in eastern European and Asian populations. It has been shown that higher incidence rates of IBD are associated with westernization. People who immigrate to westernized countries have a higher risk for developing IBD. The prevalence of IBD is also different among ethnic groups of immigrant populations. Nguyen et al. showed a higher prevalence of IBD in Non-Hispanic whites compared with Non-Hispanic blacks. The same study showed a higher ratio of IBD hospitalizations and IBDrelated mortality in Non-Hispanic blacks compared with Non-Hispanic whites. This suggests a different IBD phenotype among ethnic groups. Based on this assumption, we have investigated the clinical phenotype of CD in first and second degree Moroccan immigrants in comparison to Caucasian immigrants in the Antwerp University Hospital.
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Last date updated on July, 2014

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