alexa Hereditary Breast Cancer Scholarly Journal|OMICS International|Hereditary Genetics: Current Research

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Hereditary Breast Cancer Scholarly Journal

Breast cancer is a disease in which certain cells in the breast become abnormal and multiply without control or order to form a tumor. The most common form of breast cancer begins in cells lining the ducts that carry milk to the nipple (ductal cancer). Other forms of breast cancer begin in the glands that produce milk (lobular cancer) or in other parts of the breast. Early breast cancer usually does not cause pain and may exhibit no noticeable symptoms. As the cancer progresses, signs and symptoms can include a lump or thickening in or near the breast; a change in the size or shape of the breast; nipple discharge, tenderness, retraction and skin irritation, dimpling, or scaliness.Variations of the BRCA1, BRCA2, CDH1, STK11, and TP53 genes increase the risk of developing breast cancer. The AR, ATM, BARD1, BRIP1, CHEK2, DIRAS3, ERBB2, NBN, PALB2, RAD50, and RAD51 genes are associated with breast cancer. Cancers occur when a buildup of genetic mutations in critical genes those that control cell growth and division or the repair of damaged DNA allow cells to grow and divide uncontrollably to form a tumor. In most cases, these genetic changes are acquired during a person's lifetime and are present only in certain cells. These changes, which are called somatic mutations, are not inherited. Less commonly, gene mutations inherited from a parent increase the risk of developing cancer. In people with these inherited genetic changes, additional somatic mutations in other genes must occur for cancer to develop. Scholarly journal is a peer-reviewed journal in which scholarship relating to a particular academic discipline is published. Scholarly journals serve as forums for the introduction and presentation for scrutiny of new research, and the critique of existing research. Content typically takes the form of articles presenting original research, review articles, and book reviews. The term Scholarly journal applies to scholarly publications in all fields; this article discusses the aspects common to all academic field journals. OMICS Group is a scientific organization and online publishing house that drives the progress of research through freely available open access journals and international conferences. With 700+ peer-reviewed journals in its list and many expert reviewers and scientists in its editorial board OMICS Group is among the best open access publishers of the world. Also, OMICS Group organizes more than 3000+ International Scientific Conferences annually and provides eBooks, and additional services such as ScholarsCentral. OMICS Group has got support of more than 1000+ Scientific associations, 50,000+ editorial board members and 15 million readers.
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Last date updated on July, 2014

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