|Computational modeling and fMRI clinical study of motor cortex hand map reveal that the maps are highly dynamic, malleable representations. Shifts in the map borders are resulted from continually ongoing competitive organizing process between neuron groups that control the map borders. Alterations in the hand map can be readily brought up by manipulations of the periphery, e.g. immobilization, amputation, BoTx treatment etc. For example, even a trivial procedure such as immobilizing two fingers together by a plaster-splint for a few weeks can blur the finger borders in the motor map which become reversed and borders become clearly defined once the splint is removed. In hand muscles dystonia (Writerâs cramp), the hand motor map is displaced from its normal site.
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