Enriched neuronal cell populations are valuable tools both for basic laboratory investigations and cell therapy applications. Neuronal cells can be harvested from various sources ranging from primary neural tissue of deceased human bodies and aborted fetuses to different stem cell populations such as embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), and neural stem cells (NSCs). Supply and ethical issues associated with harvesting neuronal cells from primary neural tissue limits their clinical application, although they might greatly benefit laboratory pre-clinical studies. Pluripotent stem cells such as ESCs and iPSCs are promising sources of cells for neuronal cell therapy because of their abilities to differentiate into various neuronal cell subtypes.
A journal is a periodical publication intended to further progress of science, usually by reporting new research. Most journals are highly specialized, although some of the oldest journals publish articles, reviews, editorials, short communications, letters, and scientific papers across a wide range of scientific fields. Journals contain articles that peer reviewed, in an attempt to ensure that articles meet the journal's standards of quality, and scientific validity. Each such journal article becomes part of the permanent scientific record.
Last date updated on July, 2020