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The liver is a vital organ located in the right upper area of your abdomen under the ribs. Liver failure is a life-threatening condition in which there is a severe deterioration of liver function. Liver failure is caused by liver damage, which makes it difficult or impossible for the liver to function normally in processes that are critical to life and your overall health including Blood clotting, clearing the blood of toxins, fighting infection, removing waste, metabolizing medications and other substances etc. Treatment usually involves controlling protein consumption, limiting sodium in the diet, completely avoiding alcohol, and treating the cause, but sometimes liver transplantation is required.