Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system that is characterized by a complex immune response. Its heterogenic etiology translates into complex pathogenesis with variable types of disease manifestations and a miscellaneous range of disease progression. In most cases but not all the clinically isolated syndrome (CIS) as the first single clinical event preludes a clinically definite MS (CDMS). MS is classified into four main types of clinical courses: relapsing-remitting (RR), primary progressive (PP), secondary progressive (SP), and progressive-relapsing (PR). RRMS is the most common type of disease course and is defined by relapses of active disease and phases of remission within which the patient recovers. In most cases RRMS turns at one point into a SPMS form. In this phase of the disease activities progress continuously. However, some patients suffer continued progression of disease activity (PPMS) or suffer relapses of acute disease activities within a progressive type of clinical disease course (PRMS) Paap BK, Molecular Biomarkers in Multiple Sclerosis.
Journal of multiple sclerosis open access is a collection of articles related to this clinically isolated syndrome. The journal deals with different apects of the disease in every released issue. Some of the thrust areas of multiple sclerosis research will be discussed in the journal special issues. Articles in special issues will be based on a specific theme or title of the special issue, The major objective of special issue is to target precise topics in multiple sclerosis research and thus highlight the research advancements in this line of work
Last date updated on June, 2014