Gold nanoparticle-liposome hybrids can improve the efficiency of diagnosis by providing better detection signal contrast and biological distribution. These properties make it possible as a new biological contrast agent.Successfully constructed gold nanoshelled microcapsules, which can kill HeLa cells in vitro by exposure to 808 nm light irradiation. Meanwhile, it also can still maintain adequate acoustic properties that are required to act as an ultrasound contrast agent.The research showed that the liposome release can be initiated within seconds by irradiating hollow gold nanoshells with a NIR pulsed laser. NIR light penetrates into the tissue up to 10 cm, allowing these gold nanoparticle-liposome complexes to be addressed noninvasively within a significant fraction of the human body.The integration of nanotechnology, materials science, pharmacy, and biotechnology is bringing about advances in the medical technologies used for the diagnosis and therapy of cancer, as well as the monitoring of drug distribution. For the success of gold nanoparticleliposome hybrids nanomedicine, further studies are required. (DaweiGao,Drug Design for Cancer: Gold Nanoparticle-Liposome Hybrids for Drug Delivery and Monitoring)
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Last date updated on March, 2021